Why the One-Size-Fits-All Approach to Tinnitus is Not Successful

Although there is still no cure for chronic tinnitus, there are methods to help sufferers improve their situation and quality of life

By Maren Stropahl, PhD

The word tinnitus comes from the Latin word “tinnire,” which means “to ring,” and describes the perception of a sound without being able to attribute it to an external sound source. Therefore, this type of tinnitus is a purely subjective sensation and can only be perceived by the person affected.1 It is estimated that about 10–15% of the population experience tinnitus.^1,2 However, not all tinnitus is the same. Most people who experience tinnitus do not find it disturbing, but about 20% of people with tinnitus need clinical support to cope with the noise.³ About 2% of those affected suffer so severely that their daily lives and quality of life are significantly impaired2 (Figure 1). The coronavirus pandemic could exacerbate this effect.

The exact cause of tinnitus has not been definitively determined to date. Experts nowadays believe that tinnitus is not just a problem of the auditory organ, but originates either in the peripheral, central, or even outside auditory brain regions. It is most likely a complex interaction between central and peripheral mechanisms and is usually associated with hearing loss.^1,2 It has been shown that in the case of tinnitus, there is often abnormal overactivity of neurons in the brain and abnormal synchronous firing activity of neurons.^2,6 It seems that not only the auditory centers of the brain are affected because other cortical networks also show an alteration. Recent findings suggest that a large proportion (about 90%) of people with tinnitus have hearing loss, even if it is not always measurable.1 In addition to hearing loss, the development of tinnitus is often associated with age, increased noise exposure, and stress.^1,7

Tinnitus is considered acute if its onset is perceived within the last 3 months and chronic when it persists for more than 6 months.1 The approaches to treatment for acute and chronic tinnitus are very different; for this summary, only chronic tinnitus will be considered. The perception of the sound can be either constant or intermittent, it is often perceived either in one or both ears or inside the head. Some sufferers find it difficult to localize the sound specifically. Tinnitus can be either tonal, in which case the frequency of the sound can be precisely determined by special methods, or atonal (noisy), which corresponds more to a sound composed of several frequencies.

Tinnitus is not an actual disease but a symptom and a change in how someone perceives their own hearing. Due to suffering from tinnitus, however, a serious medical condition can develop. The affected person's suffering is usually not caused by hearing the sound, but by the negative, emotional reaction caused by the perceived sound. So far, there are no clinically applicable objective measures to diagnose tinnitus,⁸ but standardized subjective tools exist in different languages to determine tinnitus severity.

Often, the most important concern for people experiencing tinnitus is to find out where the perceived noise is coming from and whether it is related to a more severe condition. A survey has shown that more than 90% of sufferers get their first information online.⁹ Compared to hearing-impaired people, people with tinnitus seek professional support very early after the symptom onset. An analysis showed that 71% of those affected contacted a professional within the first year after the onset of tinnitus, 45% even within the first three months. Unfortunately, many sufferers who seek specialist help often experience a misguided path and rarely receive direct support.¹⁰

Most individuals who suffer from tinnitus desire a pharmacological solution that will make the tinnitus disappear or at least become quieter.^11,12 To date, there is no cure for tinnitus. However, recent studies and guidelines show that there are some successful approaches to significantly reduce the tinnitus burden and significantly improve the quality of life.¹² Through a multidisciplinary approach and individually tailored therapy, a large proportion of sufferers can learn to cope with the symptoms and lead a life without major impairment.^1,3,12,13

In recent years, international tinnitus experts have developed and published clinical guidelines to assist various medical professions in recognizing affected individuals and suggesting individualized measures for improvement (e.g., European Tinnitus Guidelines, NICE guidelines [UK], Clinical Practice Guidelines).^1,15,3 The experts agree that treating tinnitus requires an anamnesis and diagnosis to characterize the condition individually and, if necessary, exclude medical causes. The so-called tinnitus assessment is used to identify how the tinnitus affects the individual’s daily life, such as problems are falling asleep, the tinnitus occurs primarily in certain situations, or whether the tinnitus interferes with certain activities of daily living. Another prerequisite for the next management steps is the adequate education of the affected person. A person suffering from tinnitus must understand the possible causes of tinnitus, what the connections are, for example, to hearing loss, and which treatment methods are available.1 This education can take place through a counseling session or, for example, through digital offerings. It is also important to inform about circulating myths and misinformation and provide them with trustworthy sources for obtaining information.

The range of treatments for tinnitus is diverse, but not all approaches are recommended. Many methods lack systematic investigation and review of the evidence of clinical benefit. Current guidelines provide recommendations on existing treatment methods. For example, the European guideline currently recommends cognitive behavioral therapy (CBT) as the best-validated therapy for tinnitus.¹ Accordingly, CBT is currently the gold standard of tinnitus treatment and successfully improves the tinnitus burden for many sufferers.^16–21 The goal of CBT is to change maladaptive behaviors and negative associations that arise from the perception of tinnitus. This change causes sufferers to neutralize their negative perceptions of tinnitus, and thus, the symptoms have less of an impact on their lives. Access to CBT with professional guidance is often associated with long waiting times and high costs. Recent efforts to provide this therapy online and self-directed therapy are showing initial success. Internet-based CBT shows results similar to conventional CBT in the studies.^19–22

Noise therapy is one of the oldest and best-known interventions for tinnitus.¹ The term noise therapy covers very different methods, which usually aim for the tinnitus to be “masked” and thus the attention can be diverted away from the disturbing noise. Accordingly, classical noise therapy does not treat the cause of tinnitus. Still, it serves as an acute solution for the affected person to reduce the negative consequences of the tinnitus perception in certain situations. For this purpose, pleasant music or a neutral, constant noise is often used.^23,24 Although this approach is widely used, few high-quality studies sufficiently demonstrate the clinical benefit. In particular, it is impossible to say unequivocally which type of noise therapy provides the greatest benefit.¹

One type of noise therapy is the hearing aid. Hearing aids can mask the tinnitus by amplifying the surrounding sounds, thus directing attention away from the tinnitus.^25–29 Hearing aids are only recommended for tinnitus treatment when hearing loss occurs.¹ Since approximately 80-90% of tinnitus patients have some hearing loss, it is recommended that an audiological examination be performed and that both an audiogram and speech understanding be measured.1,30 Most modern hearing aids have an integrated tinnitus function to play additional neutral sounds in the background. The standard offering includes noise generators using white and or pink noise. More recent noise generators also provide modulated noise or the possibility to play back preferred noises. The evidence for the efficacy of these noise generators is not clear. However, this method has low risks when used correctly. Hearing aids with integrated tinnitus functions are, therefore, a good method to improve hearing function and additionally to have an option to influence tinnitus in everyday life.^1,29,31

Newer approaches to noise therapy go a step further and specifically target the cause of tinnitus. These include, for example, acoustic neuromodulation, which aims to alter unusual neuronal activity and cortical reorganization associated with tinnitus. An example is “notched-music” or “notched-noise” therapy, in which music or noise is filtered to eliminate the predetermined tinnitus frequency.³² This method can only be applied for tonal tinnitus, where the frequency can be determined. There have been studies that have evaluated this approach; however, the results have been inconclusive. Although it may improve some sufferers, international guidelines do not recommend this therapeutic approach.^1,14 Another example is acoustic coordinated reset neuromodulation.³³ This therapy aims to reset the abnormal synchronous firing activity of neurons. According to the studies, sufferers with this method perceive a benefit up to 12 months after therapy. A recent study showed that this form of neuromodulation achieves results similar to CBT for tinnitus.³⁴ However, based on the data available, this method is not currently recommended by the guidelines.^1,14 Other neuromodulation methods, such as transcranial electrical stimulation or bimodal stimulation, are currently being evaluated in studies, but the data are insufficient for a reliable statement.^1,35

To provide people suffering from tinnitus with the best possible treatment, the current consensus among tinnitus experts is that treatment should be individually tailored and embedded in a multidisciplinary network of specialists.^1,13,36 In audiology, hearing care professionals (HCPs) play an important role. The first point of contact for those affected is usually the general physician or the ENT doctor. After a diagnosis and medical reasons for the tinnitus have been ruled out, further steps can be planned. Since tinnitus often accompanies hearing loss, HCPs are the most logical next stop on the patient's journey. In addition, HCPs usually spend more time with the individual suffering from tinnitus and can integrate hearing care into tinnitus counseling. It is important to understand how tinnitus and hearing loss are related and why hearing aids can help tinnitus with concomitant hearing loss.^26,37 Depending on the severity of the tinnitus, further treatment steps may be necessary for those affected. HCPs with additional training can provide more in-depth counseling, such as those based on Tinnitus Retraining Therapy (TRT).³⁸ Nowadays, there are also digital or Internet-based solutions for sufferers that HCPs and physicians can recommend. A referral to an appropriate professional (ENT doctors, psychologists, or other tinnitus experts) should be recommended for the more severely affected individuals.

Many HCPs lack sufficient training in tinnitus management, which represents a gap in the current care pathway. Educational institutions and hearing aid manufacturers are currently trying to close this gap by offering courses. Tinnitus experts from clinical practice also show simple methods and standardized ways how HCPs can proceed in case of tinnitus complaints to ensure the best possible treatment for affected persons (Figure 2). HCPS must build their interdisciplinary network to treat those with more significant levels of tinnitus severity in collaboration with other experts.

A look into the future indicates that the tinnitus problem could become bigger rather than smaller due to today’s noise pollution and additional environmental influences. Even though there is no cure for tinnitus today, good approaches that significantly reduce the burden of affected individuals are available. Therefore, it is hoped that the message to sufferers that they have to “live with their tinnitus” will become less and less pronounced. Professionals should motivate the affected persons, identify which methods are available to improve their quality of life significantly, and remove the “symptom tinnitus” from the center of their lives.

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Reprinted with permission from Hearing Review (September 2023)

https://hearingreview.com/hearing-loss/tinnitus/tinnitus-therapy/why-the-one-size-fits-all-approach-to-tinnitus-is-not-successful

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