Auditory Implications in Pediatric Mild Traumatic Brain Injury: Where Do We Need to Go?

The detrimental effects of a mild traumatic brain injury (mTBI) on the paediatric population has been previously established by studies reporting that between 9%1 and 31%2 of children are still symptomatic 3 months post injury. Symptoms following mTBI in children are generally heterogenous (emotional, physical, behavioural or sensory) and their variety and duration following mTBI may make it very difficult for some children to return to school and/or regular activities.3 As returning to school and routines are usually a priority for the children and their families, proper diagnosis and management of symptoms and conditions is highly important.

Over the years, guidelines for brain injury have been published and it has become clear that not all mTBI symptoms have benefited from the same research /investigation. In fact, the vast majority of guidelines published in recent years regarding diagnosis and management of mTBI in the paediatric population include recommendations for the diagnosis and treatment/or rehabilitation of vestibular dysfunction.4,5 Unfortunately, despite the structural proximity of their respective peripheral systems, the auditory system does not benefit from the same abundance of literature. Review of guidelines for paediatrics demonstrate recommendations regarding symptoms associated with the vestibular system, but few to no recommendations are made for the auditory system.5 Studies of auditory sequelae following mTBI are rare, especially in the paediatric population. However, the available studies show that damage to the peripheral and central auditory systems are likely.6

The proximity of the vestibular and auditory peripheral systems to the brain puts them in a position where an impact to the head could result in damage to those systems.  Peripheral vestibular damage following mTBI, appears to account for approximately one-third of vestibular dysfunction following mTBI.7 Peripheral damage to the auditory system following mTBI injury could potentially cause conductive or sensorineural hearing loss.6,8

Beyond the peripheral auditory system, research has shown that impairments of centralvestibular and auditory functions can be the result of an mTBI9,10 as symptoms are observed despite the absence of damage to the periphery (an indication of the possibility of damage to the central systems). Indeed, in some cases, injury mechanisms involved in mTBI can reduce processing capacities of vestibular, auditory or other sensory information, causing difficulties relaying information between these systems and structures in the brain.11 Various symptoms may include a feeling of permanent dizziness or vestibular headaches when vestibular structures are affected9,12 while difficulty understanding in noise appears to occur when the auditory system is compromised.10,13

Difficulties with understanding in noise have been also shown in pediatric populations.13,14However, information on other central auditory functions such as temporal processing, sound localization or dichotic listening which have shown deficits in adult population is still needed.15 Other auditory dysfunctions such as tinnitus or hyperacusis have been found in adults with mTBI16,17 but have yet to be detailed in children. Questionnaires such as the Post-Concussion Symptoms Scale (PCSS)18 record that a subset of children report noise sensitivity following the injury, without greater details.2,12

Although there is a notable difference between vestibular (dizziness, vertigo, nausea) and auditory (difficulty hearing in noise, auditory hypersensitivity, tinnitus) symptoms, the nature of their effects on a child's life can be similar. Indeed, these symptoms will reduce their quality of life by hindering their return to activity or school. In a recent study,3 more than 70% of the parents surveyed reported that their children benefited from school accommodations during their recovery.

To summarize, vestibular rehabilitation is recommended by concussion management guidelines19 and demonstrates positive results and remediation of some or all vestibular symptoms.20  Despite a recognized lack of studies on the auditory system, specifically in the pediatric population, it was noted in the available studies that mTBI can have detrimental consequences on several structures of this system.6,8,10,13,14 It is therefore of the utmost importance to develop this knowledge in order to increase our understanding of the impact of a mTBI on the pediatric auditory system. Investing in this field would be instrumental in the diagnosis and would therefore allow for better symptom remediation.

References

  1. Barlow KM, Crawford S, Stevenson A, et al. Epidemiology of postconcussion syndrome in pediatric mild traumatic brain injury. Pediatrics 2010;126(2):e374-e381. doi:10.1542/peds.2009-0925
  2. Zemek R, Barrowman N, Freedman SB, et al. Clinical risk score for persistent postconcussion symptoms among children with acute concussion in the ED. JAMA 2016;315(10):1014–25.
  3. DeMatteo CA, Randall S, Lin C-YA, and Claridge EA. What comes first: return to school or return to activity for youth after concussion? maybe we don't have to choose. Frontiers Neurol 2019;10.
  4. Lumba-Brown A, Yeates KO, Sarmiento K, et al. Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild Traumatic Brain Injury Among Children. JAMA pediatrics 2018;172(11):e182853-e182853.
  5. Moore RD, Kay JJ, and Ellemberg D. The long-term outcomes of sport-related concussion in pediatric populations. Internat J Psychophysiol 2018;132(Pt A):14–24.
  6. Penn C, Watermeyer J, and Schie K. Auditory disorders in a South African paediatric TBI population: Some preliminary data. International Journal of Audiology: Internat J Audiol Impact World-Wide Audiol 2009;48(3):135–43.
  7. Brodsky JR, Shoshany TN, Lipson S, and Zhou G. Peripheral Vestibular Disorders in Children and Adolescents with Concussion. Otolaryngol Head Neck Surg 2018;159(2):365–70.
  8. Zimmerman W, Ganzel T, Windmill I, et al. Peripheral hearing loss following head trauma in children. The Laryngoscope 1993;103(1):87–91.
  9. Corwin DJ, Wiebe DJ, Zonfrillo MR, et al. Grady, Vestibular deficits following youth concussion. J Pediatr 2015;166(5):1221–25.
  10. Cockrell J and Gregory SA. Audiological deficits in brain-injured children and adolescents. Brain Injury 1992;6(3):261–66.
  11. Carman A, Ferguson R, Robert Cantu R, et al. Expert consensus document: Mind the gaps—advancing research into short-term and long-term neuropsychological outcomes of youth sports-related concussions. Nature Rev Neurol 2015;11(4):230–44.
  12. Grubenhoff JA, Kirkwood MW, Deakyne S, and Wathen J. Detailed concussion symptom analysis in a paediatric ED population. Brain Injury 2011;25(10):943–49.
  13. Thompson EC, Krizman J, White-Schwoch T, et al. Difficulty hearing in noise: a sequela of concussion in children. Brain Injury 2018;32(6):763–69.
  14. Kraus N, Thompson E, Krizman J, et al. Auditory biological marker of concussion in children. Scientific Rep 2016;6(1):39009.
  15. Werff KRV and Rieger B. Auditory and cognitive behavioral performance deficits and symptom reporting in postconcussion syndrome following mild traumatic brain injury.(Research Article). J Speech Language Hear Res 2019;62(7):2501.
  16. Assi H, Moore RD, Ellemberg D, and Hébert S. Sensitivity to sounds in sport-related concussed athletes: a new clinical presentation of hyperacusis. Scientific Rep 2018;8(1):9921–21.
  17. Landon J, Shepherd D, Stuart S, et al. Hearing every footstep: Noise sensitivity in individuals following traumatic brain injury. Neuropsychol Rehabil 2012;22(3):391–407.
  18. Howell RD, Kriz CP, Mannix LR, et al. Concussion symptom profiles among child, adolescent, and young adult athletes. Clin J Sport Med 2019;29(5):391–97.
  19. McCrory P, Meeuwisse W, Dvorak J, et al. Aubry, Consensus statement on concussion in sport-the 5(th) international conference on concussion in sport held in Berlin, October 2016. Br J Sports Med 2017;51(11):838–47.
  20. Alsalaheen BA, Mucha A, Morris LO, et al. Vestibular rehabilitation for dizziness and balance disorders after concussion. J Neurologic Phys Ther 2010;34(2):87–93.
About the authors

Fauve Duquette-Laplante, MHSc

Fauve Duquette-Laplante, MHSc completed her master’s degree in Audiology in 2017 at the University of Ottawa. Currently she is pursuing her studies in the doctoral program in rehabilitation sciences at the University of Ottawa and in the biomedical sciences program, audiology option, at the Université de Montréal. She has varied research interests such as traumatic brain injury, electrophysiology and auditory processing.

Caryn Bursch, AuD

Caryn Bursch, AuD has been working in the field of Audiology since 1987. After obtaining a Clinical Doctorate, she opened a private practice where she has chosen to focus solely on the investigation of auditory processing for children and adults. Using a multidisciplinary approach, she considers both the functional and anatomical aspects of auditory abilities to gain a complete picture of what is happening when someone is trying to listen.

Amineh Koravand, PhD

Amineh Koravand, PhD is an associate professor in the Audiology and Speech-Language Pathology program of the School of Rehabilitation Sciences, Faculty of Health Sciences at the University of Ottawa. Prof. Koravand's research deals with the relationship between the peripheral and central auditory systems in children. Her goal is to develop neurophysiological measures (biological neuromarkers) to assess the central auditory processing at subcortical and cortical level of children during early childhood, to prevent disorders while brain plasticity is still significant. Moreover, she is interested to investigate the effects of enriched auditory environment, such as musical training, singing lessons, bilingualism and/or multilingualism, on the auditory processing.